New Automated System for Manufacturing Clinical Grade Stem Cells is Introduced on The Automation Partnership Stand 50 at ESACT

With the increased global interest in manufacturing autologous and allogeneic stem cell therapies, there is a move towards developing robust equipment for manufacturing cells of consistent quality. To meet this need TAP’s technical team worked with leading academic institutes and biotech companies on detailed risk assessments to ensure CompacT CellBase can match the regulatory demands GMP compliance requires.

CompacT CellBase, based on TAP’s established CompacT SelecT™ cell culture system, is available with easy to configure cell processing protocols. This offers cell therapy manufacturers the flexibility to automate cell seeding, expansion, media changing and cell harvesting in an aseptic environment. An optional module is also available for CompacT CellBase that measures confluence and, at set thresholds, automatically begins cell harvesting, thus maintaining stem cells in an undifferentiated state without any manual intervention.

Using a CompacT CellBase reduces the number of manual processing steps and eliminates the possibility of cross contamination, which means it is ideal for producing cells for use in the clinic. The system also comes with detailed Installation Qualification (IQ), Operational Qualification (OQ) and support for Performance Qualification (PQ) procedures, making on-site validation in a GMP environment a more straightforward task.

Tim Ward, Product Manager for CompacT CellBase at TAP, states: “We are delighted to introduce our CompacT CellBase at ESACT. Manufacturers of cell therapies visiting our stand can discuss how our GMP toolbox of system enhancements and validation support provide a vital link in the quality chain to assure the CompacT CellBase will help them rapidly and reproducibly generate contamination-free stem cells for use in clinical trials.”

The Automation Partnership
Matthew Walker, Head of Communications
Tel: +44 (0) 1763 227200
Fax: +44 (0) 1763-227201
Email: matthew.walker@automationpartnership.com
www.automationpartnership.com