CHICAGO, June 1 IL-Karmanos-study
CHICAGO, June 1 /PRNewswire/ -- Physicians at the Karmanos Cancer
Institute today presented the conclusions of their study, Risk of Second Lung
Cancer in Patients with Previously Treated Lung Cancer: Analysis of the
Surveillance, Epidemiology, and End Result (SEER) Registry at the American
Society of Clinical Oncology Annual Meeting in Chicago, IL.
(http://www.newscom.com/cgi-bin/prnh/20071106/KARMANOSCANCERINSTITUTELOGO)
Karmanos' Praveen Sivakumaran, M.D., along with fellow doctors Shirish
Gadgeel, M.D., Ann Schwartz, Ph.D., Fawn Vigneau, JD, MPH, Khairul Islam,
Ph.D. and Antoinette Wozniak, M.D., conducted a retrospective analysis of lung
cancer patients in the National Cancer Institute's SEER Registry. The SEER
Program registries routinely collect data on patient demographics, primary
tumor site, tumor morphology and stage at diagnosis, first course of
treatment, and follow-up for vital status. The SEER Program is the only
comprehensive source of population-based information in the United States that
includes stage of cancer at the time of diagnosis and patient survival data.
"Our study showed patients with a history of a previously diagnosed
independent primary lung cancer have more than 2.5 times the incidence of
developing second lung primary malignancies than the general population," said
Dr. Sivakumaran.
Among the approximate 185,600 lung cancer patients found in SEER data from
1973-2001 (with follow-up through 2005), 4,087 went on to develop a second
primary lung carcinoma. The vast majority (over 66 percent) of these second
primary lung malignancies presented at advanced stages and on average
developed in greater than five years. Further examination of the data showed
female patients, younger than 50 years old were found to have the highest
incidence of developing a second lung cancer compared to the general
population.
"Our examination of the data suggests that follow-up screening for second
primary lung malignancies should be maintained over time, especially for
female patients and those under the age of 50," explains Dr. Sivakumaran.
"This is in an effort to detect these malignancies at an earlier, more easily
treatable stage.
Abstract No: 8048
The Barbara Ann Karmanos Cancer Institute
The Barbara Ann Karmanos Cancer Institute in Detroit is one of 41 National
Cancer Institute (NCI)-designated comprehensive cancer centers in the United
States. Caring for more than 6,000 new patients annually on a budget of $216
million, conducting more than 700 cancer-specific scientific investigation
programs and clinical trials, the Karmanos Cancer Institute is among the
nation's best cancer centers. Its Phase I Clinical Trials Program is one of
only 16 NCI funded programs in the country. Through the commitment of 1,000
staff, including nearly 300 faculty members, and supported by thousands of
volunteer and financial donors, the Institute strives to prevent, detect and
eradicate all forms of cancer. John C. Ruckdeschel, M.D., is the Institute's
president and chief executive officer. For more information call
1-800-KARMANOS or go to www.karmanos.org.
American Society of Clinical Oncology
ASCO is the world's leading professional organization representing
physicians who care for people with cancer. With more than 25,000 members,
ASCO is committed to improving cancer care through scientific meetings,
educational programs and peer-reviewed journals. For ASCO information and
resources, visit www.asco.org/presscenter.
SOURCE The Barbara Ann Karmanos Cancer Institute
