WASHINGTON, April 3 Using a combination of pain medications to treat migraines may be more effective than using just one type, according to a U.S. study.In the April issue of the Journal of the American Medical Association, researchers compared the effects of combining sumatriptan and naproxen sodium medications with the use of placebos and the single use of both drugs. After two hours of taking the medications, those who took sumatriptan and naproxen sodium had fewer migraine symptoms than those in the control group or those who took single treatments.The studies were conducted in nearly 3,000 people among 118 U.S. clinical centers.Migraines can cause severe headaches, nausea, vomiting and sensitivity to light and sound.The reasons for the successful treatment combination are unknown, although researchers speculated in a statement that "it might be explained by the targeting of multiple pathogenic mechanisms in migraine." Copyright 2007 by UPI